Symbol Name ID |
Sit1
suppression inducing transmembrane adaptor 1 MGI:1889342 |
Darker colors indicate more annotations |
Mouse Phenotypes | increased T cell proliferation |
thymus hyperplasia |
abnormal T cell differentiation |
abnormal T-helper 1 cell differentiation |
increased double-positive T cell number |
abnormal lymphocyte cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
increased mature gamma-delta T cell number |
lymph node hypoplasia |
abnormal cytokine secretion |
increased interferon-gamma secretion |
increased interleukin-2 secretion |
increased tumor necrosis factor secretion |
increased susceptibility to experimental autoimmune encephalomyelitis |
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Availability | Mouse Genotype | |||||||||||||||
Sit1tm1Lsmn/Sit1tm1Lsmn |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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